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I've seen ample anecdotal evidence

One study on glutathione 1200mg IV twice weekly for six weeks found a benefit over placebo for skin lightening, but these benefits faded after six months

The Topical Delivery Format: Why It Matters for Skin Research Most GHK-Cu research has used either subcutaneous injection or topical application

"Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications." Curr Neuropharmacol

Source: Prkacin et al., 2001 Multi-Organ Protection: Brain, Liver, Kidney, Lung The most comprehensive study came from Gojkovic et al

This is achieved by activating Nrf2 and TLR4, while simultaneously inhibiting NF-B activity, in the liver and thymus of piglets (Liu et al