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The study found that after IDH1 mutation, it will catalyze the massive conversion of 2-KG to tumor metabolite 2-HG, while consuming reduced NADPH
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We further evaluated the clinical relevance of these findings by analyzing the expression of ACTL6A and GCLC with a tissue microarray containing 184 GC tissue specimens
K.RheeS
Van Spitzenbergen BAK, Andrade GB, Dias ES, et al
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