Given its effects on appetite, nutrition, and metabolism, use during these periods is not recommended
Nutr Rev 2002;60:1424
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Chang, H., Tsai, C., Hsu, H., & Pang, H
Patients with chronic liver disease caused by viral hepatitis (positive serology for hepatitis B or C), excessive alcohol consumption, other causes of chronic liver disease (such as autoimmune hepatitis or hemochromatosis), and those using hepatotoxic drugsincluding glucocorticoids, methotrexate, antiretrovirals, amiodarone, tamoxifen, or estrogenswere excluded
Two patterns hold across the chart