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Given its essential role in the detoxification of lipid hydroperoxides, and its overexpression in most of myeloid malignancies, GPX4 inhibition has emerged as a promising therapeutic strategy to specifically trigger ferroptosis and eradicate myeloid leukemia cells
PubMed Central , Molecules , vol
The states largest commercial health insurer will stop covering a popular class of prescription drugs for weight loss, effective Jan
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Figure 1 The mammalian ThDP-dependent enzymes (24) include cytosolic transketolase (TKT) participating in the pentose phosphate pathway
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