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If even one amino acid is out of place, or if the sample is contaminated with solvents, salts, or incomplete fragments from the synthesis process, the results are compromised

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The serine deprivation-dependent induction is regulated by the activating transcription factor 4 (ATF4) and can be reversed by the addition of glycine and serine, but not by other amino acids like leucine or cysteine (Hamano et al., 2020)

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This may lead to life-threatening arrhythmias, ventricular fibrillation, or cardiac arrest