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In the CNS, GLP-1Rs are expressed by neurons in the hippocampus, which is known to be a cognition-related brain region, and have been observed in neocortical pyramidal neurons (Hamilton and Holscher, 2009)

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It was developed by Eli Lilly and entered the published Phase 2 program in 2023 with three parallel disease contexts: obesity, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease

M.MartinezR.Al-JoboriH.AdamsJ.TriplittC.DeFronzoR.et al (2020)

GLP-1 ,

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