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Description

Six-eight week-old male C57BL/6J mice were administered a single injection with adeno-associated virus serotype 9 (AAV) via the tail vein to induce the heart-specific Pcsk5 overexpression under the transcriptional control of the CMV promoter (5 10 11 vg in 150 L per mouse) (AAV- Pcsk5 ) or the EC-specific Pcsk5 overexpression under the transcriptional control of the Icam2 promoter (1 10 12 vg in 150 L per mouse) (AAV-EC- Pcsk5 )

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