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Description

Endotoxin alters serum-free choline and phospholipid-bound choline concentrations, and choline administration attenuates endotoxin-induced organ injury in dogs

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Abbreviations ABCG2: ATP-binding cassette super-family G member-2, AKT: Protein kinase B ALT: Alanine aminotransferase AST: Aspartate aminotransferase AML: Acute myeloid leukemia Bax: Bcl2-associated X protein Bcl-2: B-cell lymphoma 2 BCRP: Breast cancer resistance protein CAT: Catalase DNR: Daunorubicin ERK1/2: Extracellular signal-regulated kinase-1/2 EPI: Epirubicin GSH: Reduced glutathione IL-10: Interleukin-10 IL-1 : Interleukin-1beta iNOS: Inducible nitric oxide synthase LDH: Lactate dehydrogenase LDL-C: Low-density lipoprotein-cholesterol MDA: Malondialdehyde MDR: Multidrug resistance MXT: Mitoxantrone NBCs: Natural bioactive compounds NF- B: Nuclear factor- b Nrf2: Nuclear factor erythroid-2 related factor 2 NSCLC: Non-small-cell lung cancer P-gp: P-glycoprotein SOD: Superoxide dismutase TOP2: Topoisomerase II References Nitiss JL

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