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Although GLP-1RAs are well established for treating obesity, type 2 diabetes, and for reducing cardiovascular risk, their potential role in inflammatory diseases such as RA has not been clearly defined
The oral formulation (Rybelsus) reports burping in up to 2% of patients
(It would also have impaired nutrient absorption)
Novo Nordisk is expected to receive approval from the US health authorities for its oral version of the GLP-1 analogue semaglutide, so that it can be launched in the first half of 2026
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Presented for research literature review only Jia Y et al
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