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S1 (240.4 mg, 0.92 mmol) was dissolved in anhydrous dichloromethane (10 mL), cooled to 0C, and BBr3 was added (553.5 mg, 2.3 mmol), and reacted for 4 hours

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Ionescu M, Frohman LA Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog