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Glutathione-deficient mice have increased sensitivity to transplacental benzo[a]pyrene-induced premature ovarian failure and ovarian tumorigenesis.Cancer Res

mRNA relative expression was determined by 2 Ct , with -actin used as an internal reference gene

At present, glutathione has been produced on an industrial scale in the way of fermentation and enzyme catalysis processes

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Since GPxs-mediated intervention is expected to regulate mainly the peroxides-activated signaling pathways, its overall contribution for offering resistance against radiation-induced cell death may be limited [1, 8,9,10]

Following the initial rounds of therapy, the frequency of sessions may be reduced, with patients returning for periodic treatments based on their ongoing health needs and goals