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These typically improve over time as your body adjusts: Nausea Vomiting Diarrhea Constipation Stomach pain Decreased appetite Serious but Rare Side Effects These occur in less than 1% of patients but require immediate medical attention: Pancreatitis (pancreas inflammation) Gallbladder problems Kidney problems Severe allergic reactions Changes in vision Low blood sugar Severe stomach problems Cancer, whether thyroid or pancreatic, does not appear to be a significant risk based on current human research
Still, as newer medications hit the market, more options for first-line treatments are becoming available for different patient populations
While tirzepatide uses GIP to enhance insulin sensitivity and metabolic efficiency, retatrutide adds direct fat-burning stimulation through glucagon
Other considerations include if this class of medications is dropped from coverage, patients on the drugs will need to find other ways to pay for it if they want to continue, the affordability and availability of the medications, and what will the long-term impact be if patients stop taking the medications suddenly
Foundayo Foundayo is made by Eli Lilly, the same manufacturer behind the injectable GLP-1 medications Mounjaro and Zepbound
A 1 mg vial reconstituted with 2 mL of BAC water gives 500 mcg/mL
