They both work, but one appears to have an edge In a study published in September in the New England Journal of Medicine, a 25 milligram semaglutide pill led to a 16.6% reduction in weight on average over 64 weeks
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The Bottom Line The highest dose of tirzepatide is 15 mg weekly, but the smartest dose is individualized
Even patients who had already used another GLP-1 medication saw better results with tirzepatide
Individual results vary based on starting weight, metabolic health, medication adherence, and lifestyle factors
Results were not different when adjusted for BMI