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Acknowledgments The authors are grateful to Longhui Qiu from University of California, San Francisco for his useful feedback that improved this paper

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Additional comparative evidence comes from: A 2025 narrative review synthesising randomised and indirect comparison data across obesity and type 2 diabetes trials, confirming tirzepatides superiority on weight and HbA1c [2]

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Renewal Requirement Don't Miss This Under CVS Caremark's Zepbound policy (6192-C), [15] your initial weight-management approval runs 8 months