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Majzoub, Ahmad
Pramlintide is a short-acting amylin analog, which cagrilintide already covers as a long-acting version
The researchers proposed that the compounds effects on muscle function operate through boosting NAD+ levels by inhibiting NNMTs consumption of nicotinamide, more substrate is available for NAD+ synthesis via the salvage pathway, supporting mitochondrial function and energy metabolism in aged skeletal muscle
A controversial lifestyle factor that has relatively unknown cellular effects on the brain during aging is cannabis use
These effects are not well-established in controlled human trials and should be considered speculative at this stage
Free radicals arent evil - but theyre volatile
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