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calculated as the sum of reduced GSH and two times the amount of oxidized glutathione (GSH + 2 GSSG)) levels in the serum and in the tumour interstitial fluid (TIF), the extracellular compartment surrounding tumours

Research has identified effects on genes controlling antioxidant responses, inflammatory processes, and cellular repair mechanisms

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In addition to the lean and ob/ob mice, the study included 3-KO mice and WT controls obtained from genetically verified breeding colonies

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