The behavioral effects on eating are well-documented in clinical literature: Dramatically reduced portion sizes: Clinical trials show semaglutide users lose an average of 1315% of body weight and tirzepatide users 1722%, driven largely by significant reductions in portion size and overall food intake
When B12 levels are low, these signals slow down, affecting concentration, focus, and memory
Associations between plasma levels of vitamins and cataract in the Italian-American Clinical Trial of Nutritional Supplements and Age-Related Cataract (CTNS): CTNS Report #2
Reduction of GSSG to two moles of GSH is the function of glutathione reductase, an enzyme that requires coupled oxidation of NADPH
B12 injections need to be taken less frequently than oral supplements
doi: 10.1056/NEJMoa0806470 4 HolmanRRPaulSKBethelMANeilHAMatthewsDR