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It is characterized by recurrent episodes of uncontrolled eating and significant distress, and is associated with psychiatric comorbidities (e.g., depression, anxiety, and substance use) and increased metabolic risk [131]

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International Journal of Obesity, 39 (3), 424-429

To address the issue mentioned above, stimulus-responsive fluorescence imaging strategies that can activate signal light-up only in the presence of biomarkers or pathological environments can afford higher tumor-to-normal tissue ratios (T/N ratio) and real-time biological information, making the activatable modality a preferred choice for disease diagnosis and therapy evaluation [21], [22], [23], [24], [25]