RPS15 mutations have been reported to rewire the translational program of primary CLL cells, particularly affecting translational machinery and immune processes 35
Supported by studies and advanced manufacturing processes
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However, the signaling pathway for Mac-1 clustering-induced EV biogenesis by neutrophils appeared to be divergent from the signaling pathway for phagocytosis, independent of Syk and Src kinases, but dependent on PLC2 and intact calcium signaling 10
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