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10.1016/S0896-6273(00)80466-3 Neuron 115 MainaF.HiltonM
Furthermore, the mechanistic significance of these pathways, mediated by PDE1B and PDE10A, has guided medicinal chemistry efforts, which, when integrated with computational approaches, have substantially accelerated the discovery of potent, selective, and CNS-penetrant PDE1B and PDE10A inhibitors (Bhardwaj and Purohit, 2021
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Peptides carry out numerous functions in the body
By integrating peptides that target vascular healing, cytoskeletal dynamics, epithelial integrity, and extracellular matrix (ECM) remodeling, this blend supports multipathway regenerative modeling in controlled laboratory settings