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found that although androgen deprivation therapy inhibited the expression of renal glutaminase (KGA) in the GLS1 subtype, the expression of glutaminase C (GAC) was upregulated in tumor cells, which is an androgen-independent GLS1 subtype with stronger enzymatic activity
Twenty key molecular drivers involved in proteolysis and angiogenesis have been identified as potential biomarkers and therapeutic targets
These reactions contribute to metabolic efficiency
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