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32 In another casecontrol study, patients who underwent cholecystectomy had higher levels of plasma TGs, as well as higher levels of total and low-density lipoprotein cholesterol, but lower levels of high-density lipoprotein cholesterol than control subjects without GB disease or who had not undergone cholecystectomy 33 (Table 2)
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And in vitro , metformin reduces the inflammatory activation of macrophages by interfering with the metabolic changes linked to inflammation (Xiong et al., 2021)
This imbalance did not affect the primary endpoint and the incidence rate was higher in patients with a previous history of heart failure and independent of renal function at study baseline (57, 66, 67)
The expression levels of caspase-3 and Bax were significantly lower in the GO@GSH-FA-treated cells, while the expression of Bcl-2 was markedly increased
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