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[5] In the same 28-day study, DIO mice showed reduced body weight and fat mass gains alongside improved glucose tolerance and attenuated hepatic steatosis

This means concerns about long-term IGF-1 elevation do not apply to AOD 9604

Cotillard, A

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Chemical Name: Nicotinamide Adenine Dinucleotide (oxidized form)

Published in vitro and animal-model research has examined NNMT inhibition in connection with several areas of scientific interest, including adipocyte metabolism , NAD pathway regulation , mitochondrial function , and cellular energy signalling