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IPF pathogenesis is dependent upon TGF induction of IGF-1 [PMID: 32067272] Laboratory literature summary: IPF pathogenesis is dependent upon TGF induction of IGF-1

Hemoglobin alpha (Hb) The , but not , subunit of hemoglobin is expressed in ECs in resistance blood vessels, where it is concentrated in the myoendothelial junctions (MEJs) between ECs and VSMCs (Straub et al., 2012)

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it predates modern trial standards for the adult uses now marketed