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GLP-1 medications are typically initiated at low doses and increased slowly over several weeks or months, as per the product SmPC (Summary of Product Characteristics)
SURMOUNT-1 enrolled 2,539 adults with a mean baseline BMI of 38.0, and 94.5% of participants had a BMI of 30 or higher
Bioeng Transl Med 4(3):e10143
2014 Jan;99(1):148-55
That approach works until subtle hunger cues disappear and hydration and nutrient intake fragment, which can lead to weakness, nutrient gaps, and avoidable side effects
If you miss 2 or more consecutive doses, contact your healthcare provider (you may need to re-titrate)
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