Many recent studies also focus on the metabolic aspects of depression, suggesting the involvement of peripheral and central impairments in energy homeostasis, mitochondrial dysfunction, as well as disturbances in the gut-brain axis and gut microbiota dysbiosis as noteworthy factors in the pathogenesis of depression [6,7,8,9]
JAMA 331:18581860 Lean MEJ, Leslie WS, Barnes AC et al (2019) Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial
6?5, 8
Although the results obtained from these preclinical models translate to humans, different mechanisms exist in animals and humans, the investigation of which is a topic for future studies
NEW YORK Morgan Stanley Research is now projecting GLP-1 usage among US consumers will reach approximately 55 million by 2035
These medications include semaglutide, liraglutide, and dulaglutide