Gastrointestinal effects are particularly common, especially during treatment initiation and dose escalation: Nausea classified as 'very common' (affecting more than 1 in 10 patients) in the SmPC [1] [2] Vomiting 'common' (affecting up to 1 in 10 patients) Diarrhoea 'common' according to the MHRA/EMC SmPC Constipation 'common', likely related to delayed gastric emptying Abdominal pain or discomfort 'common', generally mild to moderate in severity Decreased appetite 'common', which may lead to reduced food intake and weight loss (note that while weight loss can occur with Ozempic, it is not licensed for weight management in the UK) [1] [2] These gastrointestinal symptoms usually diminish over time as the body adapts to the medication
This article explains why muscle matters, what the research shows about lean mass loss on these drugs, and the evidence-based strategies protein intake, resistance exercise, and smart monitoring that can help protect your muscle while losing weight
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What They Do GLP-1 receptor agonists (e.g., semaglutide, liraglutide
Store refrigerated and use within 28 days.
Whether youre using a GLP-1 medication or following a calorie deficit, its essential to protect your muscle mass so the weight you lose comes primarily from body fat, not muscle