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This persistent inflammation constitutes a key pathogenic factor in the progression of T2DM, further impairing insulin signaling and compromising carbohydrate metabolism ( Several studies have associated T2DM with periodontitis, suggesting a bidirectional association between both pathologies (Santos et al., 2015

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The barrier has more than one layer

It stimulates collagen and elastin production, promotes angiogenesis (new blood vessel formation), and has anti-inflammatory properties