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Post-translational modifications in heat stress-related diseases

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Amino acid sequence of the NAD (H)binding region of the mitochondrial nicotinamide [PMID: 3426633] Laboratory literature summary: Amino acid sequence of the NAD (H)binding region of the mitochondrial nicotinamide nucleotide transhydrogenase modified by

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This effect is achieved by the increased ROS formation (prooxidant effect), resulting in caspase 8 cleavage, inhibition of Janus kinase 2 (JAK2), and triggering regulator of apoptosis BAX, known as bcl-2-like protein 4

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