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It is important to note that concentration is not the only factor determining efficacy: the galenic formulation, pH and presence of cofactors significantly influence the peptide's bioavailability

Am J Emerg Med 6:104107 Rivera-Penera T, Gugig R, Davis J, McDiarmid S, Vargas J, Rosenthal P et al (1997) Outcome of acetaminophen overdose in pediatric patients and factors contributing to hepatotoxicity