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Cellular and Molecular Gastroenterology and Hepatology, 13 (5), 14741476
Faster Results: The synergy between glutathione and alpha arbutin accelerates visible improvement in dark spots and acne marks
Evaluation: Body fat (DXA scanning) Lean mass Insulin sensitivity Energy expenditure What they found: The combination showed an additive effect on fat reduction vs monotherapy AOD-9604 partially protected lean mass during GLP-1-induced weight reduction Increased energy expenditure in combination (~3 % vs GLP-1 alone) No new safety signals Why it matters: It validates the concept of combination , the idea that AOD-9604 may not work on its own, but can add value in combination with incretin agonists
However, identifying impaired vitamin B12 status in the earlier stages is more challenging, but can be enhanced by using one or more plasma biomarkers of B12 status
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I would not prescribe something simply because it becomes accessible
