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Serum levels miss intracellular depletion in 3040% of cases

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They prepared soybean phosphatidylcholine (PC) monolayers loaded with 7-DHC and found that 7-DHC is preferentially oxidised in vitro and that the oxidation of 7-DHC in vitro is critical for the inhibition of (phospho)lipid peroxidation

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While genetic predisposition does not predict exact medication response or guarantee that symptoms will occur, understanding these variants may help explain individual variation in side effect patterns