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The studies conducted by Mansur et al 23 and Li et al 22 and their respective findings on liraglutides effect on cognitive function are promising, as they observed improvements in cognitive scores and memory, along with enhanced brain activation, indicating the potential neurocognitive benefits of GLP-1 agonists
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The group of GPx enzymes, which play an irreplaceable role in the regulation of ROS homeostasis in vivo, has been thought to use GSH as a reducing agent to catalyze the reduction of H 2 O 2 or organic peroxides to generate water or corresponding alcohols, respectively [17]
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The American Diabetes Association recommends maintaining individualized A1c targets while avoiding rapid glucose reduction, which may temporarily worsen neuropathic symptoms
