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In the STEP-1 clinical trial, adults using semaglutide 2.4 mg weekly with lifestyle intervention lost an average of 14.9% body weight over 68 weeks, compared to 2.4% in the placebo group
Comparison of the results between men and women was, however, not conducted as this was not considered meaningful because of the limited sample size
Tests for low renal function include BUN, creatinine, GFR, albumin, insulin, HgA1c, and urinalysis
With that said, some healthcare providers may prescribe lower doses for patients who are particularly sensitive to gastrointestinal effects or who have struggled to stay on treatment at standard doses
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