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To identify specific microbial taxa involved, the team studied fecal samples from the mice

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Scott et al

Beyond weight outcomes, the Phase 2 obesity trial also reported improvements in several cardiometabolic markers, including: Reductions in waist circumference Improvements in fasting glucose and insulin sensitivity Favourable changes in blood pressure and lipid profiles Phase 3 trials understood to form part of the TRIUMPH programme are now underway, evaluating retatrutide in broader populations including people with type 2 diabetes and cardiovascular disease

Int.J Sport Nutr.Exerc.Metab 2011;21(5):385-397