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This improvement in body composition is an important therapeutic goal because increased lean soft tissue mass is associated with increased insulin sensitivity 30 , improved metabolic health and increased life expectancy 31
Functional brain imaging studies have reported a decrease in synaptic connectivity and neuronal circuitry in the PFC and hippocampus in depressed patients (Perlman et al., 2012
Surgery also has stronger metabolic effects
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Peptide protocols, volume 1
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