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3.4 Reliability test Data extraction for this review was carried out independently by two reviewers (the authors) using a tailored extraction form (Excel sheet), developed in alignment with established best practices in systematic reviews
The pathophysiology of NAFLD involves complex interactions between insulin resistance, lipotoxicity, oxidative stress, and inflammatory pathways
What most people don't realize is that the true root cause of these challenges often lies deeper than calorie intake or exercise routines
GLP-1 treatment for diabetes and obesity Semaglutide, a GLP-1 receptor agonist, is the active ingredient in Ozempic for diabetes and in Wegovy for obesity
Its evidence base includes the STEP program for weight management, published in The New England Journal of Medicine in 2021
Diabetologia 65 , 411423 (2022)
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