The absorption rate of the drug
Circulation 101:207213 Ohara M, Ogawa K, Suda G, Kimura M, Maehara O, Shimazaki T, Suzuki K, Nakamura A, Umemura M, Izumi T, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ohnishi S, Sakamoto N (2018) L-Carnitine suppresses loss of skeletal muscle mass in patients with liver cirrhosis
Transparency and education are key parts of that process
Others: Roche, J&J, Sanofi, and AZ have had GLP-1 efforts (some deprioritized) or new dual/triple agonists in development (e.g., Roches pipeline includes a dual agonist announced in 2024)
The gene at chromosome 17p13.3 encoding for the human GLP-2 receptor is also very well conserved as the rat sequence is 80% of the same amino acid sequence (Shin et al., 2005)
These findings highlight the critical role of THC-induced oxidative stress as a contributing factor to cannabinoid-mediated neuropsychiatric risk and identifies a novel antioxidant treatment candidate for the prevention and/or reversal of these pathophysiological outcomes