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To be clear, none of the enrolled participants reported liver-related side effects, symptoms, or liver failure

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The terminal methyl group is a thioether, which generally cannot form a permanent dipole within the molecule and retains low solubility

However, certain forms of the supplement may not be absorbed well, so its important to find a bioavailable form

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Fatal liver damage can usually be prevented if the initial dose of NAC is administered within 8-12 hours of an APAP overdose