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Chronic constipation About 614% of the general population suffers from chronic constipation for which no clear cause can be found

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Patients should always follow the instructions provided by their healthcare provider and pharmacy label

Development of targeted protein degradation therapeutics

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In this population: Higher waist-to-hip ratio increased risk up to 7.7-fold (especially peri-menopausally) Greater body fat percentage, waist-height ratio, or visceral fat area each increased risk around 4-fold Higher body mass index (BMI) or waist circumference, each, increased risk almost 3-fold Because obesity is associated with significant changes in immunometabolic and hormonal parameters, it seems likely that the strength of these findings will be confirmed in other populations