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If you have deep scarring, we recommend seeking professional treatments like microneedling, chemical peels, and laser therapy under your dermatologists recommendation

Even slight changes in diet, hydration, or activity can affect your progress

Patients should also have a clear plan for what happens if the medication is stopped, changed, unavailable, not tolerated, or no longer needed

A 2025 meta-analysis of 23 trials found berberine reduced body weight by less than 2 pounds and BMI by about half a point statistically significant but far less dramatic than prescription weight-loss medications

We must acknowledge that our experience with these weight loss drugs is limited, and tens of millions of people may be exposed to their unforeseen effects for decades