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Low blood sugar (hypoglycemia) : This is more common in patients who are also taking other diabetes medications
The physiologic advantage disappears
Med Oncol
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Mechanistically it adds steric and electrostatic bulk at the same end of the molecule the binding proteins engage, deepening the reduction in affinity beyond what the single substitution achieves alone
Redox homeostasis maintained by GPX4 facilitates STING activation
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