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Importantly for the tirzepatide context, the effects on fat mass were more pronounced than the effects on total body weight, suggesting that levocarnitine may indeed shift the composition of weight loss toward greater fat loss

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Accordingly, several studies have reported a positive correlation between plasma DPP-4 activity and fasting plasma glucose or HbA1c (68, 72), although it should be borne in mind that an association does not necessarily reflect a causative relationship