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AOD9604 does not compete for the hGH receptor and nor does it induce cell proliferation, unlike hGH
This suggests that the phenol ring is most favorable due to its significant hydrophilic and hydrophobic interactions, while the amine and amide groups, being polar, offer hydrogen bonding interactions
Placebo consisted of the vehicle (20 mmol/L sodium phosphate buffer, pH 6.5, 1% sucrose and 4% d-mannitol
J Biol Chem (2012) 287:4016172
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