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Both groups reported improvements of cognitive functions, sensory neuropathy, and vibration sense, but there was no statistical significant difference between both groups

DOI: 10.1161/HYP.0000000000000065 Wimalasena K (2011): Vesicular Monoamine Transporters: Structure-Function, Pharmacology, and Medicinal Chemistry

As part of an overarching feature called the "Detox Guides," the website touted the $135 Implant-O-Rama, a device used to give oneself a coffee enema at home, as a means to "Supercharge Your Detox." But the concept of detoxing the idea of flushing toxins from the body through a special diet or procedure has been widely dismissed as pseudoscience

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These studies indicate that the function of the insulin/IGF-1 pathway is abundantly regulated at the receptor level

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