Interim analysis of the EAGLE trial: an open-label study to assess the long-term safety and tolerability of bardoxolone methyl in patients with alport syndrome: PO1300
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The New England Journal Of Medicine 2026 PMID: 42253238, DOI: 10.1056/nejmoa2600751.Peer-Reviewed Original ResearchCitationsAltmetricConceptsGlucagon-like peptide-1Dose escalation periodPlacebo groupEarly discontinuationBody weightTreatment of adultsDouble-blind trialPhase 2 trialBaseline to weekObesity-related complicationsManagement of obesityObesity medicationsBody-mass indexMean BMIPlaceboEfficacy analysisNo deathsAdverse eventsCardiometabolic benefitsMean body weightGastrointestinal symptomsLifestyle modificationParticipantsEnd pointsAdults Oral small molecule GLP-1 receptor agonist aleniglipron in people with overweight or obesity: a randomized, double-blind, placebo-controlled phase 2b trial Rosenstock J, Lingvay I, Ryan D, Jastreboff A , Kushner R, Acosta A, Blevins T, Choi M, Holmes F, Smith T, Connery L, Li Y, Liu M, Barth A, Butcher J, Civitarese A, Yue H, Coll B
KPV is especially known for helping regulate inflammation, which can support faster and more efficient recovery
Read the Medication Guide and Instructions for Use that come with Ozempic for additional information