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The body focuses on cellular regeneration during sleep

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J Neurochem 73:390399 Kannan R, Yi JR, Tang D, Li Y, Zlokovic BV, Kaplowitz N (1996) Evidence for the existence of a sodium-dependent glutathione (GSH) transporter

When long term stress occurs, unlike other physiologic functions (homeostatic), the stress response often stays up-regulated even after the stressful situation is resolved