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While almost all newborns with SCD may now be expected to survive to adulthood in medium- to well-resourced countries, 75% or more of neonates with SCD die before they turn five in Sub-Saharan Africa
A phase 3 trial of a higher-dose CagriSema formulation at 2.4/7.2 mg is planned for initiation in the second half of 2026, and the REDEFINE 11 trial, exploring CagriSemas full weight-loss potential, is expected to report data in the first half of 2027
The accumulating data of animal experimentation involving interventions targeting ferroptosis are promising in terms of the perspective of the symptoms reversal and inhibition of the disease progression [238]
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