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Curli protein binds to and activates TLR2, leading to an increase in intracellular -syn, which in turn triggers a neuroinflammatory response through the TLR2/MyD88/NF-B pathway (18, 19)

Certain therapies discussed may be investigational and are not approved by the FDA for the diagnosis, treatment, cure, or prevention of disease

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Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance