Causes: Allopurinol, phenytoin, isoniazid, quinine, penicillin, quinidine Vascular lesions [edit] These result from injury to the vascular endothelium
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[18] Gene-expression profiling shows it upregulates collagen types I, III, and IV and suppresses MMPs, mirroring retinol's effects via separate mechanisms
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Direct NAD+ IV Tolerability A small 2026 commercial-infusion study reported short-term tolerability data and variable exploratory metabolic outcomes, with more research needed beyond 30 days